Calcium channel blocker overdose: Experience with amlodipine

Calcium channel blocker overdose: Experience with amlodipine

Amlodipine overdose is only scarcely reported from India. We report two cases of near fatal Amlodipine overdose managed in our ICU with fluid, vasopressors, calcium infusion and Glucagon. Literature is reviewed and other treatment modalities discussed.

Calcium-Channel Blocker Overdose

1522-8401/$ see fro doi:10.1016/j.cpem.2 Department of Eme Children’s Hospit RI 02903, USA. Reprint requests and Department of E Children’s Hospit RI 02903, USA. Calcium-channel blockers (CCB) were first developed in the 1960s. Since then, the list of formulations and variety of uses has increased significantly. Unfortunately, toxic exposures to CCBs have also increased since their debut. This ...

Severe Overdose of Calcium Channel Blocker and Successful Management: A Literature Review and Case Report

Spermatogenesis following discontinuation of calcium channel blocker amlodipine in rats.

BACKGROUND The calcium channel blockers are commonly associated with male infertility. Long-term administration of such drugs has been shown to suppress spermatogenesis. The present study was designed to determine the effects of cessation of calcium channel blocker (amlodipine) medication on spermatogenesis. METHODS The study was carried out in the Department of Physiology, in collaboration w...

Case report: drug-induced gingival overgrowth associated with the use of a calcium channel blocker (amlodipine).

INTRODUCTION Many factors can contribute to the development of gingival overgrowth (hyperplasia), including: plaque control; periodontal variables; medications and their relative dose; age; sex; and, genetic factors. Nifedipine is a calcium channel blocker commonly reported to result in drug-induced gingival overgrowth (DIGO). This report outlines a case of gingival overgrowth induced by amlodi...